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“DMSO’s Effect On HSV-1 and 2” DMSO blocks productive infection in vitro in different cell types with a 50% inhibitory concentration (IC50) from 0.7 to 2% depending upon the multiplicity of infection. The concentration dependence exhibits a Hill coefficient greater than 1, indicating that DMSO blocks productive infection by acting at multiple different points (mechanisms of action) with positive cooperativity. Consistently, we identified at least three distinct temporal target mechanisms for inhibition of virus growth by DMSO. At late stages of infection, DMSO reduces virion infectivity, and markedly inhibits viral DNA replication. A third mode of action was revealed using an oligonucleotide-based DNA microarray system for HSV. These experiments showed that DMSO reduced the transcript levels of many HSV-1 genes; including several genes coding for proteins involved in forming and assembling the virion. Also, DMSO markedly inhibited some but not all early transcripts indicating a previously unknown mode for inhibiting the early phase of HSV transcription-replication cycle Complete study at http://www.biomedcentral.com/1471-2334/2/9 “Absorption of Liquid Stabilized Oxygen” Research Reference: In a small study conducted at Martin Microscope by James D. Aker (February 2, 1998), Stabilized oxygen was given to test subjects sublingually. The product was tagged with a radioactive isotope of iodine, which has an affinity only for free, bio-available oxygen. This isotope will not bond to molecules containing oxygen, only free-oxygen. Within 90 seconds after taking the product, all the subjects demonstrated the presence of free oxygen tagged by this isotope in the blood stream indicating that liquid stabilized oxygen does contain free oxygen and that this oxygen can be absorbed into the blood stream sublingually “O2 Plus™ (ASO®) has been tested on U.S. Marines in a double blind study” Research Reference: In a controlled double blind study conducted by the U.S. Naval Warfare Training Center (San Diego, CA) and the University of Utah (Nutrition Department) it was found that O2 Plus™ (ASO®) group experienced greater stamina and endurance, reduced muscle fatigue, more energy, a greater feeling of strength and better performance than did the placebo group. “The Effect of a Liquid Oxygen Supplement (O2 Plus™ ®) on the Arterial Partial Pressure of Oxygen in Normal and Hypoxic Guinea Pigs.” Subjects: 60 Guinea Pigs. Publication: March 2001, Kasr El-Aini Medical Journal Summary: The (O2 Plus™ ®) supplementation resulted in significant elevation of arterial blood - oxygen levels in both normal and hypoxic guinea pigs. Conclusions: Not only did (O2 Plus™ ®) increase blood - oxygen levels, but it also may help to improve oxygen transportation in the body. Several other conditions may benefit from (O2 Plus™ ®) use, such as: 1) pre-term infants with bronchopulmonary displasia; 2) anti-tumor therapy; and 3) humans with cystic fibrosis, congestive heart failure, bronchial asthma and chronic hypoxia. Athletes may also benefit (O2 Plus™ ®) use. “Value of Stabilized Oxygen (O2 Plus™ ®)) In the treatment of hypoxemia.” Publication: April 2001, The Journal of Chest Diseases and Tuberculosis. Subjects: 60 human patients suffering from hypoxaemia. 30 patients had COPD and 30 patients had IPF. Summary: IPF: highly significant increase of blood-oxygen level (Pao2) over baseline level. IPF: after two-week stoppage, the oxygen level was still significantly higher than baseline. COPD: highly significant increase of blood-oxygen level over baseline level. COPD: after two-week stoppage, there was only an insignificant decrease in the oxygen level. The control groups without (O2 Plus™ ®) ® continued to have low Pao2. No adverse side effects were noticed. Well tolerated by all patients, without exception. Conclusions: (O2 Plus™ ®) could be a good replacement for home use of oxygen tanks. Can be used safely with patients having renal or liver impairments. Can be an alternative to standard hypoxemia therapy. Increases tissue oxygenation and improves aerobic oxidation, resulting in better use of nutrients, yielding more energy, improved mental concentration, and improved quality of life. *The Food and Drug Administration has not reviewed or evaluated the above studies and the compilation of the studies herein is not intended to offer a diagnosis, cure or prevention for any disease. (O2 Plus™ ®) is reporting the terms and findings of the independent studies described above. O2 Plus™ (ASO®) Toxicity Study Research Reference: Toxicity studies were conducted on O2 Plus™ (ASO®) by SGS U.S. Testing Company, Inc. and completed in January of 1998. The results of the acute dermal toxicity (Kligman Skin Sensitization) and Acute Dermal Irritation/Corrosion Test, acute oral toxicity (LD5O Limit Test), eye irritation and inhalation toxicity (Acute Inhalation LC5O Toxicity Limit Test) studies were conclusive. O2 Plus™ (ASO®) is not a toxic substance. All animals used in the above tests showed consistent weight gain when subjected to ASO® indicating that ASO® does not interfere with normal metabolic functions. “These administered doses (of ASO®) are generally regarded as acute bench mark doses and the reported findings suggested that the submitted sample (of ASO®), when tested as specified, was not considered to be toxic by the appropriate agencies. In addition, that there was general weight gain in most test animals further supports the conclusion.” Dr. Charles C. Tong, Ph.D., D.A.B.T. |
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Disclaimer: DMSO is approved by the FDA for Interstitial Cystitis - a disease occuring mostly in children. Off label use is therefore permitted. Stabilized liquid oxygen is on the FDA's GRAS list - Generally Regarded As Safe. Statements about DMSO and O2 Plus™ made herein have not been evaluated by the FDA. Nova Net Enterprise, LLC does not intend to diagnose, treat, cure or prevent disease. We offer suggestions based on past experience, extensive educated knowledge plus customer feedback and testimonials.
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